Preheat oven to 425 degrees F. Spray a 9x13 baking dish with non-stick cooking spray; set aside.
Take biscuits out of can and separate. One by one, flatten each biscuit with your hands or a rolling-pin.
Place a few pepperoni pieces, mozzarella and Parmesan cheeses, then a few more pepperoni pieces.
Gather up the edges until sealed. Lay seam side down in the prepared baking dish.
Continue until all biscuits are completed. Then brush tops with egg.
Sprinkle the biscuits with remaining Parmesan cheese, Italian seasoning and garlic powder.
Bake for 15-18 minutes, or until golden. If you noticed the tops are getting a little to brown, cover with a foil tent until they are done.
Serve immediately with pizza sauce and enjoy!